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Dr. Richard Youle, recipient of the 2021 Breakthrough Prize in Life Sciences, has made groundbreaking discoveries in understanding Parkinson’s disease. Leading a research team at the NIH’s National Institute of Neurological Disorders and Stroke, Youle’s work has focused on how genetic mutations in the PINK1 and Parkin genes contribute to the disease. Parkinson’s is linked to a failure in the brain's ability to dispose of damaged mitochondria, which are the cell's energy producers. Youle’s resear
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