This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

DNA has tremendous potential as a data storage medium, but the process of synthesizing DNA from scratch is time-consuming. It has to be done one nucleotide at a time in a specific sequence. New ...

The developed probe exclusively reacts with mitochondrial DNA repair intermediates and modulates the DNA repair and degradation processes, reducing mitochondrial DNA loss. When environmental stress ...

In August 2017, the National Natural Science Foundation of China (NSFC) launched the Major Research Plan “Dynamic Modifications and Chemical Interventions of Biomacromolecules” (implementation period ...

Collaborating researchers have made a breakthrough discovery regarding the intricate defense systems of bacteriophages (phages)—viruses that can specifically target harmful bacteria without harming ...

From synthetic biology and gene therapy to data storage and biofuel production, the demand for synthetic DNA is rising. (1) Chemicals remove the 5’-hydroxyl protecting group. The nucleosides are rich ...

Researchers have discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development. This finding ...

In the rapid and fast-growing world of nanotechnology, researchers are continually on the lookout for new building blocks to push innovation and discovery to scales much smaller than the tiniest speck ...

Researchers have unveiled a way to flip genes back on without slicing into the genome, a shift that could make CRISPR far ...